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Deep dive into applications of the Cyto-Mine platform & challenges in cartridge manufacturing record

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Permanente

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Dott.ssa Maryam Ahmadi

Dr. Maryam Ahmadi, Director of Cellular & Molecular Biology at Sphere Fluidics, brings over 17 years of comprehensive experience in both industry and academia to her role. With a decade-long tenure at a Contract Research Organization (CRO), Maryam honed her skills in managing diverse projects. Notably, as the former Director of Bioassay at Abzena, she led a team specializing in bespoke Immunology and Bioassay for external clients. Her responsibilities included the development of service lines crucial for testing and de-risking therapeutics, such as PK studies, MHC-associated peptide proteomics (MAPPs), and Cytokine Release Assay for therapeutic antibodies and antibody-drug conjugates. Maryam's expertise spans Immunology and Tumour Biology, underscored by her proficiency in designing and overseeing tailored R&D initiatives. Her academic journey includes a postdoctoral research position at University College London (UCL), where she delved into tumour-specific immune responses. She holds a PhD in Tumour Immunology from the University of Bristol, UK.

Sig. Daniel Horner

Daniel Horner joint the Statec Consumables team beginning of 2012. He was member of the project management team, leading various projects from early stage development to mass production. Since two years he strengthens the team for new technologies and processes. His background is electrical engineering.

Programma

The following topics will be addressed:

Sphere Fluidics:  the Cyto-Mine® platform 

  • Contribution of Sphere Fluidics to the single cell market
  • Cyto-Mine® workflow & capabilities
  • Applications like cell line development, antibody discovery, synethic biology, cell engineering & cell therapy


STRATEC Consumables: cartridge manufacturing

  • History of development stages: from proof of principle to a final cartridge design
  • Core microfluidic elements of the Cyto-Mine® cartridge like encapsulation, incubation & sorting
  • Manufacturing steps of Cyto-Mine® cartridge from molding, bonding, laser welding to special elements like valves & electrodes